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Barrier Code ingredientų vertinimai remiasi šiuose šaltiniuose surinktais duomenimis: 662 moksliniais straipsniais, 158 saugos vertinimais ir Europos Sąjungos teisės aktais. Visi jie išvardyti šiame puslapyje.

Kaip naudojame šaltinius

Kas yra šaltinis

Šaltinis yra recenzuojamas mokslinis leidinys arba institucijos dokumentas: Europos Komisijos ir jos mokslinių komitetų nuomonės, saugos vertinimai, farmakopėjos, klinikinių draugijų gairės, medicinos ir dermatologijos žurnalų straipsniai, sisteminės apžvalgos.

Šaltiniais nelaikome tinklaraščių, prekės ženklų puslapių, ingredientų portalų, parduotuvių aprašymų ir dirbtinio intelekto santraukų.

Paieškos sistema nėra šaltinis

PubMed, Scopus ir panašios sistemos padeda straipsnį surasti. Šaltinis visada yra žurnalas, kuriame straipsnis paskelbtas. Leidinys turi būti įtrauktas bent į vieną pripažintą mokslinių leidinių rodyklę arba būti įvardytos institucijos leidinys.

Kiekvienas įvertinimas atsekamas

Perskaitytą šaltinį saugome savo archyve kartu su pažodine citata, kuria remiamės. Taip kiekvieną įvertinimą galima patikrinti: kas parašyta, kur ir kokiomis sąlygomis tirta.

Kiekvienam klausimui — tinkamas šaltinis

  • Ar ingredientas leidžiamas, ribojamas ar draudžiamas — tik pagal Europos Sąjungos teisės aktus.
  • Ar ingredientas dirgina ar sukelia alergiją — pagal saugos vertinimus ir klinikinius tyrimus.
  • Ką ingredientas daro odai — pagal jo chemiją, funkciją ir veikimo mechanizmą, aprašytą moksliniuose straipsniuose.

Tyrimo kokybę įvertiname, o ne atmetame tyrimą

Kiekvienam tyrimui užrašome, kas jame tirta: kiek žmonių, ar buvo palyginimas, kokia koncentracija, kokia odos būklė. Šie trūkumai nurodomi šalia išvados, bet tyrimo neišbraukia. Gamintojo finansuotas tyrimas vertinamas taip pat, pagal jo dizainą; finansavimas pažymimas.

Kai tyrimo nėra

Ne kiekvienam ingredientui yra atliktas tyrimas. Tada įvertinimas remiasi ingrediento chemija ir veikimo mechanizmu, o tai pažymime. Atsiradus tyrimui, jis pakeičia tokį įvertinimą. Tai, kad tyrimo neradome, nedaro produkto prastesnio.

Atsargumo kryptis

Kad ingredientą įvertintume palankiau, reikia įrodymų. Atsargesnis įvertinimas gali remtis pagrįstu samprotavimu, nes klaidingas nuraminimas vartotojui kainuoja daugiau nei perdėtas atsargumas.

Teisės aktai ir registrai

Europos Sąjungos teisės aktai ir dokumentai 8
  1. Tarybos direktyva 76/768/EEB dėl valstybių narių įstatymų, susijusių su kosmetikos gaminiais, suderinimo. OL L 262, 1976-09-27, p. 169.
  2. Europos Parlamento ir Tarybos reglamentas (EB) Nr. 1223/2009 dėl kosmetikos gaminių (nauja redakcija). OL L 342, 2009-12-22, p. 59. Naudojami II (draudžiamos medžiagos), III (ribojamos medžiagos), IV (dažikliai), V (konservantai) ir VI (UV filtrai) priedai.
  3. Europos Parlamento ir Tarybos reglamentas (EB) Nr. 1272/2008 dėl cheminių medžiagų ir mišinių klasifikavimo, ženklinimo ir pakavimo (CLP), VI priedas — suderinta klasifikacija.
  4. Komisijos reglamentas (ES) Nr. 655/2013, kuriuo nustatomi bendri teiginių apie kosmetikos gaminius pagrindimo kriterijai. OL L 190, 2013-07-11, p. 31.
  5. Komisijos reglamentas (ES) 2017/776, kuriuo dėl prisitaikymo prie technikos ir mokslo pažangos iš dalies keičiamas Reglamentas (EB) Nr. 1272/2008 (10-asis CLP pritaikymas).
  6. Komisijos reglamentas (ES) 2023/1545, kuriuo iš dalies keičiamas Reglamentas (EB) Nr. 1223/2009 dėl kvapiųjų alergenų ženklinimo kosmetikos gaminiuose. OL L 188, p. 1.
  7. Komisijos reglamentas (ES) 2023/2055 dėl sintetinių polimerų mikrodalelių (REACH XVII priedas).
  8. Darbo grupės kosmetikos teiginiams techninis dokumentas „Technical document on cosmetic claims“ (2017-07-03 redakcija).
Kitų institucijų dokumentai 8
  1. JAV maisto ir vaistų administracija (FDA). Guidance for Industry: Labeling for Cosmetics Containing Alpha Hydroxy Acids. 2005.
  2. FDA. Alpha Hydroxy Acids; Beta Hydroxy Acids (informaciniai puslapiai apie kosmetikos ingredientus). 2022.
  3. FDA. Over-the-Counter (OTC) Monograph M017: External Analgesic Drug Products for Over-the-Counter Human Use. 2023.
  4. FDA / DailyMed. Differin (adapalene) gel; Retin-A (tretinoin) cream and gel — vaisto informacinis lapelis. 2024.
  5. OECD. SIDS Initial Assessment Report for SIAM 14: Linalool. 2002.
  6. Europos cheminių medžiagų agentūra (ECHA). REACH registracijos dokumentacija: linalool (EC 201-134-4).
  7. NITE (Japonija). GHS Classification Result — Linalool. 2012.
  8. NICNAS (Australija). Common skin sensitisers. 2005.

Registrai ir standartai

  • CosIng — Europos Komisijos kosmetikos ingredientų duomenų bazė (ingredientų funkcijos, nuorodos į reglamento priedus).
  • IFRA standartai (Tarptautinė kvapiųjų medžiagų asociacija): Nr. 032 trimetilbenzenpropanolis, 037 geraniolis, 063 metiljononas, 067 ąžuolų kerpių ekstraktai, 080 medžių kerpių ekstraktai, 097 serenčių aliejus ir absoliutas, 151 hidroabietilo alkoholis, 184 pušinių augalų dariniai, 186 limonenas, 187 linalolis; IFRA standartų taikymo gairės (51-asis pakeitimas).
  • PubChem — JAV nacionalinės medicinos bibliotekos cheminių medžiagų registras (medžiagos tapatybė ir fizikinės savybės).

Saugos vertinimai

Dokumentų iš viso: 158.

SCCS — ES Vartotojų saugos mokslinis komitetas 26Nepriklausomų mokslininkų komitetas, rengiantis nuomones Europos Komisijai apie kosmetikos ingredientų saugą (įskaitant ankstesnius ES komitetus).
  1. SCC (Scientific Committee on Cosmetology). S66: 4-tert-Butyl-4′-methoxydibenzoylmethane. Opinion, 50th plenary meeting. 1992.
  2. SCCNFP. Position paper concerning the safety of alpha-hydroxy acids. SCCNFP/0370/00. 2000.
  3. SCCNFP. Opinion concerning the determination of certain formaldehyde releasers in cosmetic products. SCCNFP/586/02. 2002.
  4. SCCNFP. Updated position paper concerning consumer safety of alpha-hydroxy acids. SCCNFP/0799/04. 2004.
  5. SCCS. Opinion on the mixture of 5-chloro-2-methylisothiazolin-3(2H)-one and 2-methylisothiazolin-3(2H)-one. SCCS/1238/09. 2009.
  6. SCCS. Opinion on Quaternium-15 (cis-isomer). SCCS/1344/10. 2011.
  7. SCCS. Opinion on fragrance allergens in cosmetic products. SCCS/1459/11. 2012.
  8. SCCS. Opinion on methylisothiazolinone (P94), submission II (sensitisation only). SCCS/1521/13, revision of 27 March 2014. 2014.
  9. SCCS. Opinion on the safety of the use of formaldehyde in nail hardeners. SCCS/1538/14. 2014.
  10. SCCS. Opinion on α-arbutin. SCCS/1552/15. 2015.
  11. SCCS. Opinion on methylisothiazolinone (MI) (P94), submission III (sensitisation only). SCCS/1557/15. 2015.
  12. SCCS. Opinion on phenoxyethanol. SCCS/1575/16. 2016.
  13. SCCS. Opinion on skin sensitisation quantitative risk assessment for fragrance ingredients (QRA2). SCCS/1589/17. 2018.
  14. SCCS. Opinion on the safety of aluminium in cosmetic products, submission II. SCCS/1613/19. 2020.
  15. SCCS. Opinion on benzophenone-3. SCCS/1625/20. 2021.
  16. SCCS. Opinion on homosalate. SCCS/1622/20. 2021.
  17. SCCS. Opinion on octocrylene. SCCS/1627/21. 2021.
  18. SCCS. Scientific advice on the threshold for the warning „contains formaldehyde“ in Annex V, preamble point 2, for formaldehyde-releasing substances. SCCS/1632/21. 2021.
  19. SCCS. Revision of the scientific opinion (SCCS/1576/16) on vitamin A (retinol, retinyl acetate, retinyl palmitate). SCCS/1639/21. 2022.
  20. SCCS. Opinion on the safety of alpha-arbutin and beta-arbutin in cosmetic products. SCCS/1642/22. 2023.
  21. SCCS. The SCCS Notes of Guidance for the testing of cosmetic ingredients and their safety evaluation, 12th revision. SCCS/1647/22. 2023.
  22. SCCS. Opinion on salicylic acid. SCCS/1646/22. 2023.
  23. SCCS. Opinion on benzyl salicylate. SCCS/1656/23. 2023.
  24. SCCS. Opinion on methylparaben. SCCS/1652/23, corrigendum February 2024. 2024.
  25. SCCS. Scientific advice on the safety of diethylamino hydroxybenzoyl hexyl benzoate (DHHB, S83). SCCS/1678/25. 2025.
  26. SCCS. Scientific opinion on tea tree oil. SCCS/1681/25. 2025.
CIR — Kosmetikos ingredientų peržiūra (JAV) 132Nepriklausoma ekspertų grupė, vertinanti kosmetikos ingredientų saugą.
  1. Cosmetic Ingredient Review. Final Report of the Safety Assessment for PEG-75 Lanolin, PEG-20 Lanolin, PEG-27 Lanolin, PEG-30 Lanolin, PEG-40 Lanolin, PEG-50 Lanolin. 1982.
  2. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Carbomers-934, -910, -934P, -940, -941, and -962. 1982.
  3. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Myristyl Myristate and Isopropyl Myristate. 1982.
  4. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Squalane and Squalene. 1982.
  5. Cosmetic Ingredient Review. Final Report on the Safety Assessment of PEG-2, -6, -8, -12, -20, -32, -40, -50, -100, and -150 Stearates. 1983.
  6. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Candelilla Wax, Carnauba Wax, Japan Wax, and Beeswax. 1984.
  7. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Fossil and Synthetic Waxes. 1984.
  8. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Butyl Stearate, Cetyl Stearate, Isobutyl Stearate, Isocetyl Stearate, Isopropyl Stearate. 1985.
  9. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Stearyl Alcohol, Oleyl Alcohol, and Octyl Dodecanol. 1985.
  10. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Cholesterol. 1986.
  11. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Hydroxyethylcellulose, Hydroxypropylcellulose, and Related Cellulose Ethers. 1986.
  12. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Phenyl Trimethicone. 1986.
  13. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid. 1987.
  14. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Retinyl Palmitate and Retinol. 1987.
  15. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Sodium Sesquicarbonate, Sodium Bicarbonate, and Sodium Carbonate. 1987.
  16. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol, and Behenyl Alcohol. 1988.
  17. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Polyquaternium-10. 1988.
  18. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Jojoba Oil and Jojoba Wax. 1992.
  19. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Sodium Cocoyl Isethionate. 1993.
  20. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Bisabolol. 1999.
  21. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Lecithin and Hydrogenated Lecithin. 2001.
  22. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trilinolein. 2001.
  23. Cosmetic Ingredient Review. Final report on the safety assessment of Arnica montana extract and Arnica montana. Int J Toxicol. 2001. PubMed 11558636 · doi:10.1080/10915810160233712
  24. Cosmetic Ingredient Review. Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. Int J Toxicol. 2001. PubMed 11766131 · doi:10.1080/10915810152630729
  25. Cosmetic Ingredient Review. Final report on the safety assessment of Malic Acid and Sodium Malate. Int J Toxicol. 2001. PubMed 11358110 · doi:10.1080/109158101750300946
  26. Cosmetic Ingredient Review. Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium. 2002.
  27. Cosmetic Ingredient Review. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan. Int J Toxicol. 2002. PubMed 12537931 · doi:10.1080/10915810290169819
  28. Cosmetic Ingredient Review. Final Report of the Safety Assessment of Niacinamide and Niacin. 2005.
  29. Cosmetic Ingredient Review. Final Report of the Safety Assessment of Urea. 2005.
  30. Cosmetic Ingredient Review. Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. Int J Toxicol. 2005. PubMed 16154915 · doi:10.1080/10915810590953851
  31. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Sodium p-Chloro-m-Cresol, p-Chloro-m-Cresol, Chlorothymol, Mixed Cresols, m-Cresol, o-Cresol, p-Cresol, Isopropyl Cresols, Thymol, o-Cymen-5-ol, and Carvacrol. 2006.
  32. Cosmetic Ingredient Review. Amended Final Report on the Safety Assessment of Glyceryl Dilaurate, Glyceryl Diarachidate, Glyceryl Dibehenate, Glyceryl Dierucate, Glyceryl Dihydroxystearate, Glyceryl Diisopalmitate, Glyceryl Diisostearate, Glyceryl. 2007.
  33. Cosmetic Ingredient Review. Final Report on the Safety Assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid. 2007.
  34. Cosmetic Ingredient Review. Final Report of the Cosmetic Ingredient Review Expert Panel Safety Assessment of Glycyrrhiza Glabra (Licorice) Rhizome/root. 2008.
  35. Cosmetic Ingredient Review. Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Polyisobutene and Hydrogenated Polyisobutene as Used in Cosmetics. 2008.
  36. Cosmetic Ingredient Review. Final Report of the Safety Assessment of Alcohol Denat., Including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the Denaturants. 2008.
  37. Cosmetic Ingredient Review. Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate. Int J Toxicol. 2009. PubMed 19636067 · doi:10.1177/1091581809337738
  38. Cosmetic Ingredient Review. Final Report of the Safety Assessment of Allantoin and Its Related Complexes. 2010.
  39. Cosmetic Ingredient Review. Final report of the Cosmetic Ingredient Review Expert Panel amended safety assessment of Calendula officinalis-derived cosmetic ingredients. Int J Toxicol. 2010. PubMed 21164072 · doi:10.1177/1091581810384883
  40. Cosmetic Ingredient Review. Amended Final Safety Assessment Diethanolamides as Used in Cosmetics. 2011.
  41. Cosmetic Ingredient Review. Final Safety Assessment On the Safety Assessment of Alkyl Glyceryl Ethers As Used in Cosmetics. 2011.
  42. Cosmetic Ingredient Review. Amended Safety Assessment of Alkyl Esters as Used in Cosmetics. 2012.
  43. Cosmetic Ingredient Review. Final Amended Report On the Safety Assessment of Ethanolamides as Used in Cosmetics. 2012.
  44. Cosmetic Ingredient Review. Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Methyl Acetate. 2012.
  45. Cosmetic Ingredient Review. Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of cocamidopropyl betaine (CAPB). Int J Toxicol. 2012. PubMed 22869896 · doi:10.1177/1091581812447202
  46. Cosmetic Ingredient Review. Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics. 2012.
  47. Cosmetic Ingredient Review. Safety Assessment of Cyclomethicone, Cyclotetrasiloxane, Cyclopentasiloxane, Cyclohexasiloxane, and Cycloheptasiloxane. 2012.
  48. Cosmetic Ingredient Review. Safety Assessment of Dimethicone Crosspolymers as Used in Cosmetics. 2012.
  49. Cosmetic Ingredient Review. Safety Assessment of Panax spp. Root-Derived Ingredients as Used in Cosmetics. 2012.
  50. Cosmetic Ingredient Review. Safety Assessment of α-Amino Acids as Used in Cosmetics. 2012.
  51. Cosmetic Ingredient Review. Amended Safety Assessment of Achillea Millefolium-Derived Ingredients as Used in Cosmetics. 2013.
  52. Cosmetic Ingredient Review. Safety Assessment of Ammonium Hectorites as Used in Cosmetics. 2013.
  53. Cosmetic Ingredient Review. Safety Assessment of Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics. 2013. doi:10.1177/1091581813497764
  54. Cosmetic Ingredient Review. Safety Assessment of Isoparaffins as Used in Cosmetics. 2013.
  55. Cosmetic Ingredient Review. Safety assessment of alkyl glyceryl ethers as used in cosmetics. Int J Toxicol. 2013. PubMed 24174475 · doi:10.1177/1091581813497766
  56. Cosmetic Ingredient Review. Safety Assessment of Anthemis Nobilis-Derived Ingredients as Used in Cosmetics. 2014.
  57. Cosmetic Ingredient Review. Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics. Int J Toxicol. 2014. PubMed 24861367 · doi:10.1177/1091581814526891
  58. Cosmetic Ingredient Review. Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics. 2014.
  59. Cosmetic Ingredient Review. Safety Assessment of Tripeptide-1, Hexapeptide-12, their Metal Salts and Fatty Acyl Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics. 2014.
  60. Cosmetic Ingredient Review. Safety Assessment of Alkyl Esters as Used in Cosmetics. 2015.
  61. Cosmetic Ingredient Review. Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics. 2015.
  62. Cosmetic Ingredient Review. Safety Assessment of Galactomannans as Used in Cosmetics. 2015.
  63. Cosmetic Ingredient Review. Safety Assessment of Glycerin as Used in Cosmetics. 2015.
  64. Cosmetic Ingredient Review. Safety Assessment of Lecithin and Other Phosphoglycerides as Used in Cosmetics. 2015.
  65. Cosmetic Ingredient Review. Safety Assessment of Polysaccharide Gums as Used in Cosmetics. 2015.
  66. Cosmetic Ingredient Review. Amended Safety Assessment of Chamomilla Recutita-Derived Ingredients as Used in Cosmetics. 2016.
  67. Cosmetic Ingredient Review. Re-Review Summary 40th Anniversary Overview and Rereview Summaries From 2011 to 2015. 2016.
  68. Cosmetic Ingredient Review. Safety Assessment of Methyl Glucose Polyethers and Esters as Used in Cosmetics. 2016.
  69. Cosmetic Ingredient Review. Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics. 2016.
  70. Cosmetic Ingredient Review. Amended Safety Assessment of Isethionate Salts as Used in Cosmetics. Int J Toxicol. 2017. PubMed 28553736 · doi:10.1177/1091581816685552
  71. Cosmetic Ingredient Review. Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. 2017.
  72. Cosmetic Ingredient Review. Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate. Int J Toxicol. 2017. PubMed 29243541 · doi:10.1177/1091581817728996
  73. Cosmetic Ingredient Review. Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics. 2017.
  74. Cosmetic Ingredient Review. Safety Assessment of Ethers and Esters of Ascorbic Acid as Used in Cosmetics. 2017.
  75. Cosmetic Ingredient Review. Safety Assessment of Plant-Derived Fatty Acid Oils. 2017.
  76. Cosmetic Ingredient Review. Amended Safety Assessment of Mentha piperita (Peppermint)-Derived Ingredients as Used in Cosmetics. 2018.
  77. Cosmetic Ingredient Review. Safety Assessment of Alkane Diols as Used in Cosmetics. 2018.
  78. Cosmetic Ingredient Review. Safety Assessment of Alkyl Betaines as Used in Cosmetics. 2018.
  79. Cosmetic Ingredient Review. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. 2018.
  80. Cosmetic Ingredient Review. Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics. 2018.
  81. Cosmetic Ingredient Review. Amended Safety Assessment of Parabens as Used in Cosmetics. 2019.
  82. Cosmetic Ingredient Review. Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics. 2019.
  83. Cosmetic Ingredient Review. Safety Assessment of Alkyl Phosphates as Used in Cosmetics. 2019.
  84. Cosmetic Ingredient Review. Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics. 2019.
  85. Cosmetic Ingredient Review. Safety Assessment of Brown Algae-Derived Ingredients as Used in Cosmetics. 2019.
  86. Cosmetic Ingredient Review. Safety Assessment of Camellia sinensis–Derived Ingredients As Used in Cosmetics. 2019.
  87. Cosmetic Ingredient Review. Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics. 2019.
  88. Cosmetic Ingredient Review. Safety Assessment of Fatty Acid Amidopropyl Dimethylamines as Used in Cosmetics. Int J Toxicol. 2019. PubMed 31170841 · doi:10.1177/1091581819836089
  89. Cosmetic Ingredient Review. Safety Assessment of Fatty Acids & Fatty Acid Salts as Used in Cosmetics. 2019.
  90. Cosmetic Ingredient Review. Safety Assessment of Glycerin as Used in Cosmetics. Int J Toxicol. 2019. PubMed 31840548 · doi:10.1177/1091581819883820
  91. Cosmetic Ingredient Review. Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics. 2019.
  92. Cosmetic Ingredient Review. Safety Assessment of PCA (2-Pyrrolidone-5-Carboxylic Acid) and Its Salts as Used in Cosmetics. 2019.
  93. Cosmetic Ingredient Review. Safety Assessment of Sorbitan Esters as Used in Cosmetics. 2019.
  94. Cosmetic Ingredient Review. Squalane and Squalene — Re-Review Summary. 2019.
  95. Cosmetic Ingredient Review. Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics. 2020.
  96. Cosmetic Ingredient Review. Safety Assessment of Ceramides as Used in Cosmetics. 2020.
  97. Cosmetic Ingredient Review. Safety Assessment of Monoglyceryl Monoesters as Used in Cosmetics. Int J Toxicol. 2020. PubMed 33203266 · doi:10.1177/1091581820966951
  98. Cosmetic Ingredient Review. Safety Assessment of Polyaminopropyl Biguanide (Polyhexamethylene Biguanide Hydrochloride) as Used in Cosmetics. 2020.
  99. Cosmetic Ingredient Review. Safety Assessment of Inorganic Hydroxides as Used in Cosmetics. 2021.
  100. Cosmetic Ingredient Review. Safety Assessment of Saccharide Esters as Used in Cosmetics. 2021.
  101. Cosmetic Ingredient Review. Amended Safety Assessment of Malic Acid and Sodium Malate as Used in Cosmetics. Int J Toxicol. 2022. PubMed 35993419 · doi:10.1177/10915818221117535
  102. Cosmetic Ingredient Review. Amended Safety Assessment of Triglycerides as Used in Cosmetics. 2022.
  103. Cosmetic Ingredient Review. Safety Assessment of Acrylamide/Acrylate Copolymers as Used in Cosmetics. 2022.
  104. Cosmetic Ingredient Review. Safety Assessment of Ethers and Esters of Ascorbic Acid as Used in Cosmetics. Int J Toxicol. 2022. PubMed 35549580 · doi:10.1177/10915818221093545
  105. Cosmetic Ingredient Review. Safety Assessment of Glyceryl Acrylates as Used in Cosmetics. 2022.
  106. Cosmetic Ingredient Review. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol. 2022. PubMed 36177798 · doi:10.1177/10915818221124809
  107. Cosmetic Ingredient Review. Safety Assessment of Phenyl-Substituted Methicones as Used in Cosmetics. 2022.
  108. Cosmetic Ingredient Review. Safety Assessment of Plant-Derived Proteins and Peptides as Used in Cosmetics. 2022.
  109. Cosmetic Ingredient Review. Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides as Used in Cosmetics. 2022.
  110. Cosmetic Ingredient Review. Safety Assessment of Alkyl Sultaines as Used in Cosmetics. 2023.
  111. Cosmetic Ingredient Review. Safety Assessment of Cocos nucifera (Coconut)-Derived Ingredients as Used in Cosmetics. Int J Toxicol. 2023. PubMed 36862031 · doi:10.1177/10915818231157751
  112. Cosmetic Ingredient Review. Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics. 2023.
  113. Cosmetic Ingredient Review. Safety Assessment of Hyaluronates as Used in Cosmetics. 2023.
  114. Cosmetic Ingredient Review. Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics. 2023.
  115. Cosmetic Ingredient Review. Amended Safety Assessment of Lanolin and Lanolin-Derived Ingredients as Used in Cosmetics. 2024.
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Odos barjeras 25Raginio sluoksnio sandara, barjero lipidai (ceramidai, cholesterolis, riebalų rūgštys), vandens netekimas per odą, barjero atsistatymas.
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  9. Hirata K, Mohammed D, Hadgraft J, Lane ME. Influence of lidocaine hydrochloride and penetration enhancers on the barrier function of human skin. Int J Pharm. 2014;477(1-2):416-20. PubMed 25305378 · doi:10.1016/j.ijpharm.2014.10.012
  10. Kakuda L, Melo MO, Campos PMBGM. Hydrolipidic Characteristics and Clinical Efficacy of a Dermocosmetic Formulation for the Improvement of Homeostasis on Oily Mature Skin. Life (Basel). 2022;13(1). PubMed 36676036 · doi:10.3390/life13010087
  11. Kauth M, Trusova OV. Topical Ectoine Application in Children and Adults to Treat Inflammatory Diseases Associated with an Impaired Skin Barrier: A Systematic Review. Dermatol Ther (Heidelb). 2022;12(2):295-313. PubMed 35038127 · doi:10.1007/s13555-021-00676-9
  12. Kono T, Miyachi Y, Kawashima M. Clinical significance of the water retention and barrier function-improving capabilities of ceramide-containing formulations: A qualitative review. J Dermatol. 2021;48(12):1807-1816. PubMed 34596254 · doi:10.1111/1346-8138.16175
  13. Li N, Styczynski P, Gibb R, Li C, Marsh R. Study on percutaneous penetration of representative cosmetic ingredients in a baby wipe product in an in vitro diaper rash skin model. Toxicol In Vitro. 2024;100:105912. PubMed 39069215 · doi:10.1016/j.tiv.2024.105912
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Drėkikliai 38Glicerinas, karbamidas, hialurono rūgštis, propandiolis, betainas, pantenolis — kaip jie sulaiko vandenį odoje.
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Emolientai ir okliuzinės medžiagos 18Vazelinas, skvalanas, silikonai, augaliniai aliejai ir sviestai, vaškai, esteriai.
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Tekstūra ir pojūtis ant odos 15Kaip emolientai jaučiasi ant odos, lengvos ir sunkios tekstūros, tinkamumas riebiai odai.
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Prausikliai ir paviršinio aktyvumo medžiagos 94Natrio laurilsulfatas ir kitos stiprios medžiagos, švelnūs prausikliai, muilas ir sintetiniai prausikliai, medžiagos, mažinančios prausiklio poveikį odai.
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Kvapiosios medžiagos ir eteriniai aliejai 60Kvapieji alergenai, jų oksidacija laikui bėgant, nuplaunami ir ant odos paliekami produktai, eterinių aliejų poveikis odai.
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Vėsinančios medžiagos 22Mentolis, kamparas ir kitos medžiagos, sukeliančios vėsumo ar dilgčiojimo pojūtį.
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Konservantai 43Metilizotiazolinonas, formaldehido išskyrikliai, parabenai, fenoksietanolis, benzilo alkoholis, produktai „be konservantų“.
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Kontaktinė alergija 43Odos jautrinimas, lopų mėginių tyrimų tinklų Europoje ir Šiaurės Amerikoje duomenys, alergija pažeistame barjere.
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Odos dirginimas 11Dirginimo tyrimai su savanoriais, kartotinio naudojimo poveikis, kelių medžiagų dirginimas kartu.
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Rūgštys ir šveitimas 29Glikolio, pieno, salicilo rūgštys, polihidroksi rūgštys, cheminiai pilingai, mechaninis šveitimas.
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Retinoidai 42Retinolis ir jo dariniai, tretinoinas, adapalenas — poveikis odai, dirginimas, naudojimas.
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Vitaminas C ir antioksidantai 25Askorbo rūgštis ir jos dariniai, jų stabilumas, vitaminas E ir kiti antioksidantai.
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Niacinamidas 27Poveikis barjerui, riebalų išsiskyrimui, spuogams ir paraudimui.
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Azelaino rūgštis 18Spuogai, rozacėja, pigmentinės dėmės.
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Spuogai ir porų kimšimas 44Medžiagos, kurios gali užkimšti poras, tyrimų modeliai, prausikliai ir priežiūra spuogams linkusiai odai.
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Paraudimas ir rozacėja 16Paraudimą mažinančios ir jį sukeliančios medžiagos, jautri oda.
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  8. Maggioni D, Cimicata A, Praticò A, Villa R, Bianchi FM, Busoli Badiale S, et al. A Preliminary Clinical Evaluation of a Topical Product for Reducing Slight Rosacea Imperfections. Clin Cosmet Investig Dermatol. 2020;13:299-308. PubMed 32368125 · doi:10.2147/CCID.S240784
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Pigmentinės dėmės 8Arbutinas, kojo rūgštis, traneksamo rūgštis ir kitos šviesinančios medžiagos.
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Peptidai ir raukšlės 32Peptidai, kolageną veikiančios medžiagos, odos senėjimas.
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Apsauga nuo saulės 19UV filtrai, jų dirginimas ir alergija, fototoksiškumas, apsaugos nuo saulės naudojimas.
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Raminančios medžiagos ir augaliniai ekstraktai 8Azijinė centelė, avižos, alantoinas, bisabololas, alavijas, medetkos, ramunėlės ir kiti ekstraktai.
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Sausa ir atopinė oda 20Emolientų terapija, atopinis dermatitas, odos sausumas.
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Priežiūros rutinos derinimas 5Kurias aktyvias medžiagas galima naudoti kartu, kurias geriau atskirti ryte ir vakare.
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